Mucoadhesive In Situ Rectal Gel Loaded with Rifampicin: Strategy to Improve Bioavailability and Alleviate Liver Toxicity

Although it is a front-line in tuberculosis treatment, rifampicin (RF) exhibits poor oral bioavailability and hepatotoxicity.Rectal mucoadhesive and in situ rectal gels were developed to overcome drug drawbacks.A RF/polyethylene glycol 6000 co-precipitate was first prepared in TurboFlo II Parts different ratios.Based on the drug solubility, the sel

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Variations in dung beetles assemblages (Coleoptera: Scarabaeidae) within two rain forest habitats in French Guiana

The structure of dung Board Game/Gently Used Games/Mattel beetle communities inhabiting tropical forests are known to be sensitive to many kinds of environmental changes such as microclimate related to vegetation structure.I examined Scarabaeinae assemblages in two sites of undisturbed high forest and two sites of low forest forming a transitional

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